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Enter the currency designation that "you", the site owner, are using on your site to accept payments from your visitors to place listings, register, or whatever other fee-based features you may be offering to them. In other words, when you set up your "pricing" you will be asked to enter a "price" (the cost) for your visitors to place listings on your site. That "price" is in a numerical format, such as "3". So, the Currency Designation field on this page defines what "3" actually mean. i.e. US Dollars, British Pounds, etc. You are telling the software how to treat your "price" entries that you make.
Note that just because you are only entering "one" Currency Designation on this page, doesn't mean that you can't accept other forms of currency. In fact, you can still accept most currencies, as it really just depends upon your Payment Processor (PayPal, Authorize.net, etc.) When you set up your merchant account, you will specify at that time your currency of choice. Then, during their listing process, the visitor will be automatically taken to your Payment Gateway, pay in "their" currency, which will then be automatically converted to "your" currency. This may sound complicated, but it actually all takes place behind the scenes, and there really isn't much for you to do.
<tip c n>Do not confuse the functionality and intent of this page with that of Currency Types.</tip>
If you are having trouble getting currency symbols to display properly on your site, you have a couple of options: